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The inability to deal with short half-time of drug substances with prolonged disease treatment and variations in plasma/blood levels resulted in increased daily dosing and reduced patient's compliance. Therefore, SEPS Pharma develops controlled drug release and long-acting formulations based on lipophilic and/or self emulsifying prodrug systems resulting in prolonged delivery of a drug while maintaining its blood concentration within therapeutic limits and providing for greater effectiveness in the treatment of chronic conditions.
The advantages of controlled delivery systems and long-acting formulations are:
• Maintenance of optimum therapeutic drug concentration in the blood or in a cell
• Predictable and reproducible release rates for extended periods of time
• Enhancement the activity duration for short half-time drugs
• The elimination of side effects, frequent dosing, waste of drug, optimised therapy
• Better patient's compliance
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